WebHistone H3 is a nuclear protein and a component of the nucleosome core that is essential for organizing genomic DNA in eukaryotic nuclei. 1 It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications, including citrullination. WebNov 17, 2024 · PurposeAcute pancreatitis (AP) is an inflammatory disease. AP starts with sterile inflammation and is often complicated with critical local or systemic infection or sepsis in severe cases. Septic AP activates peptidyl arginine deiminase (PAD) and citrullinates histone H3 (CitH3), leading to neutrophil extracellular trap (NET) formation. Investigating …
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WebAn ELISA for quantifying Citrullinated Histone H3 in biological matrices.Enzyme-linked immunosorbent assays identify and calculate substances such as proteins, peptides, antibodies, and hormones. The provided reagents and supplies allow personnel to combine an immobilized antigen with an antibody that is joined to an enzyme. Following with … WebJan 9, 2024 · The CitH3 mAb (4 Cit) significantly improved mouse survival compared to the LPS + mouse IgG group (p = 0.0004) and to the LPS + CitH3 mAb (3 Cit) group (p = 0.0039). There was no survival ... dart brand salt and sanctuary
Citrullinated histone H3, a biomarker of neutrophil
WebAnti-Histone H3 (citrulline R2 + R8 + R17) antibody [RM1001] (ab281584) Research with confidence – consistent and reproducible results with every batch. Long-term and … Web小鼠瓜氨酸组蛋白H3(CitH3)酶联免疫吸附检测试剂盒 货号:ELK9874 规格:96T (本试剂盒仅供体外研究使用,不用于临床诊断) 灵敏度:0.118ng/mL 检测范围:0.32-20ng/mL 特异性:可检测重组或天然的小鼠 Cit H3,且不与其它相关蛋白交叉反应 试剂盒组成 中文名称 … WebThis product is a recombinant antibody that recognizes Human CITH3. The monoclonal antibody reacts with the epitope of CITH3. It cross-reacted with Mouse CITH3. … dart bray to pearse