WebABSTRACTEmbryo implantation is effected by a myriad of signaling cascades acting on the embryo–endometrium axis. Here we show, by using MALDI TOF analysis, far-western analysis and colocalization and co-transfection studies, that STAT3 and MCL-1 are WebAbstract Glutathione (GSH), an abundant nonprotein thiol antioxidant, participates in several biological processes and determines the functionality of stem cells. A detailed understanding of the molecular network mediating GSH dynamics is still lacking. Here, we show that activating transcription factor-2 (ATF2), a cAMP-response element binding protein …
3D genome organization around nuclear speckles drives mRNA …
Web1 apr. 2024 · Nuclear speckles/IGCs are one of the most prominent nuclear bodies, yet their functional significance remains largely unknown. Recent advances in sequence … Web4 uur geleden · Besides MSC components, we found several proteins with predominantly nuclear localization in the nuclear ArgRS interactome, including the nuclear speckle and spliceosome component SRRM2 (Fig. 2a,b ... grey smith heritage auctions
Nuclear speckles: dynamic hubs of gene expression regulation
Web核スペックル:バイオキーワード集|実験医学online:羊土社 核スペックル 核質のクロマチン間に存在し,前駆体mRNAスプライシング因子を多く含む核内構造体.1細胞あた … Web16 feb. 2024 · The authors propose a model in which high splicing factor concentration at nuclear speckles, with elevated affinity for pre-mRNA, drives RNA pol II (pre-mRNA)-dense regions to the speckle’s periphery, shaping genome organization and acting as splicing catalyzers. In other words, shaping genome organization through transcription (high RNA … WebThe nucleus of pre-implantation mammalian embryos is characterized by peculiar structural organization. At the initial stages of cleavage, the nucleus of the embryo contains the so … greysmith employment ri